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In vitro and in vivo characterization of DNA delivery using recombinant Lactococcus lactis expressing a mutated form of L. monocytogenes Internalin A

BACKGROUND: The use of food-grade Lactic Acid Bacteria (LAB) as DNA delivery vehicles represents an attractive strategy to deliver DNA vaccines at the mucosal surfaces as they are generally regarded as safe (GRAS). We previously showed that either native Lactococcus lactis (LL) or recombinant invasi...

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Detalles Bibliográficos
Autores principales:	de Azevedo, Marcela, Karczewski, Jurgen, Lefévre, François, Azevedo, Vasco, Miyoshi, Anderson, Wells, Jerry M, Langella, Philippe, Chatel, Jean-Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541092/ https://www.ncbi.nlm.nih.gov/pubmed/23253484 http://dx.doi.org/10.1186/1471-2180-12-299

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