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Maraviroc, a CCR5 Antagonist, Prevents Development of Hepatocellular Carcinoma in a Mouse Model

Chronic liver disease may result in a sequential progression through fibrosis, cirrhosis and lead, eventually, to hepatocellular carcinoma (HCC). Hepatic stellate cells (HSC) seem to be responsible for the fibrogenic response through the activation of an autocrine loop involving the chemokine recept...

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Detalles Bibliográficos
Autores principales: Ochoa-Callejero, Laura, Pérez-Martínez, Laura, Rubio-Mediavilla, Susana, Oteo, José A., Martínez, Alfredo, Blanco, José R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541191/
https://www.ncbi.nlm.nih.gov/pubmed/23326556
http://dx.doi.org/10.1371/journal.pone.0053992