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Association of age at menarche with metabolic syndrome and its components in rural Bangladeshi women

BACKGROUND: Early age at menarche is associated with increased risk of metabolic syndrome in both China and the West. However, little is known about the impact of age at menarche and metabolic syndrome in South Asian women, including those from low-income country, where age at menarche is also falli...

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Autores principales: Akter, Shamima, Jesmin, Subrina, Islam, Mazedul, Sultana, Sayeeda Nusrat, Okazaki, Osamu, Hiroe, Michiaki, Moroi, Masao, Mizutani, Taro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541253/
https://www.ncbi.nlm.nih.gov/pubmed/23140264
http://dx.doi.org/10.1186/1743-7075-9-99
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author Akter, Shamima
Jesmin, Subrina
Islam, Mazedul
Sultana, Sayeeda Nusrat
Okazaki, Osamu
Hiroe, Michiaki
Moroi, Masao
Mizutani, Taro
author_facet Akter, Shamima
Jesmin, Subrina
Islam, Mazedul
Sultana, Sayeeda Nusrat
Okazaki, Osamu
Hiroe, Michiaki
Moroi, Masao
Mizutani, Taro
author_sort Akter, Shamima
collection PubMed
description BACKGROUND: Early age at menarche is associated with increased risk of metabolic syndrome in both China and the West. However, little is known about the impact of age at menarche and metabolic syndrome in South Asian women, including those from low-income country, where age at menarche is also falling. The aim of the present study was to investigate whether age at menarche is inversely associated with metabolic syndrome in Bangladeshi women, who are mostly poor and have limited access to and or poor health care facilities. METHODS: This community-based cross-sectional study was performed using 1423 women aged between 15–75 years from rural Bangladesh in 2009 and 2010. Metabolic syndrome was defined according to standard NCEP-ATP III criteria. Logistic regression was used to estimate the association between age at menarche and metabolic syndrome, with adjustment of potential confounding variables, including age, education, marital status, tobacco users, use of contraceptives and number of pregnancies. RESULTS: Early onset of menarche (<12 years) as compared to late onset (>13 years) was found to be associated with a higher prevalence of metabolic syndrome (odds ratio=1.55; 95 % confidence interval =1.05-2.30). Age at onset of menarche was also inversely associated with prevalence of high triglycerides (P for trend <0.01) and low high-density lipoprotein cholesterol (P for trend = 0.01), but positively associated with prevalence of high fasting blood glucose (P for trend =0.02). However, no significant association was found between age at menarche, high blood pressure and elevated waist circumference. CONCLUSION: Early onset of menarche might promote or trigger development of metabolic syndrome. Thus, knowledge of the history of age at onset of menarche may be critical in identifying women at risk of developing metabolic syndrome and those likely to benefit the most from early interventions.
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spelling pubmed-35412532013-01-11 Association of age at menarche with metabolic syndrome and its components in rural Bangladeshi women Akter, Shamima Jesmin, Subrina Islam, Mazedul Sultana, Sayeeda Nusrat Okazaki, Osamu Hiroe, Michiaki Moroi, Masao Mizutani, Taro Nutr Metab (Lond) Research BACKGROUND: Early age at menarche is associated with increased risk of metabolic syndrome in both China and the West. However, little is known about the impact of age at menarche and metabolic syndrome in South Asian women, including those from low-income country, where age at menarche is also falling. The aim of the present study was to investigate whether age at menarche is inversely associated with metabolic syndrome in Bangladeshi women, who are mostly poor and have limited access to and or poor health care facilities. METHODS: This community-based cross-sectional study was performed using 1423 women aged between 15–75 years from rural Bangladesh in 2009 and 2010. Metabolic syndrome was defined according to standard NCEP-ATP III criteria. Logistic regression was used to estimate the association between age at menarche and metabolic syndrome, with adjustment of potential confounding variables, including age, education, marital status, tobacco users, use of contraceptives and number of pregnancies. RESULTS: Early onset of menarche (<12 years) as compared to late onset (>13 years) was found to be associated with a higher prevalence of metabolic syndrome (odds ratio=1.55; 95 % confidence interval =1.05-2.30). Age at onset of menarche was also inversely associated with prevalence of high triglycerides (P for trend <0.01) and low high-density lipoprotein cholesterol (P for trend = 0.01), but positively associated with prevalence of high fasting blood glucose (P for trend =0.02). However, no significant association was found between age at menarche, high blood pressure and elevated waist circumference. CONCLUSION: Early onset of menarche might promote or trigger development of metabolic syndrome. Thus, knowledge of the history of age at onset of menarche may be critical in identifying women at risk of developing metabolic syndrome and those likely to benefit the most from early interventions. BioMed Central 2012-11-09 /pmc/articles/PMC3541253/ /pubmed/23140264 http://dx.doi.org/10.1186/1743-7075-9-99 Text en Copyright ©2012 Akter et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Akter, Shamima
Jesmin, Subrina
Islam, Mazedul
Sultana, Sayeeda Nusrat
Okazaki, Osamu
Hiroe, Michiaki
Moroi, Masao
Mizutani, Taro
Association of age at menarche with metabolic syndrome and its components in rural Bangladeshi women
title Association of age at menarche with metabolic syndrome and its components in rural Bangladeshi women
title_full Association of age at menarche with metabolic syndrome and its components in rural Bangladeshi women
title_fullStr Association of age at menarche with metabolic syndrome and its components in rural Bangladeshi women
title_full_unstemmed Association of age at menarche with metabolic syndrome and its components in rural Bangladeshi women
title_short Association of age at menarche with metabolic syndrome and its components in rural Bangladeshi women
title_sort association of age at menarche with metabolic syndrome and its components in rural bangladeshi women
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541253/
https://www.ncbi.nlm.nih.gov/pubmed/23140264
http://dx.doi.org/10.1186/1743-7075-9-99
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