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SorLA is a molecular link for retromer-dependent sorting of the Amyloid precursor protein
Deficiency in the retromer sorting pathway is known to be associated with the onset of Alzheimer disease (AD), and has been suggested to involve regulation of Amyloid precursor protein (APP) trafficking. Absence of the APP sorting receptor sorLA is also associated to AD, as amyloidogenic processing...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541330/ https://www.ncbi.nlm.nih.gov/pubmed/23740096 http://dx.doi.org/10.4161/cib.21433 |