Mitochondrial Telomerase Protects Cancer Cells from Nuclear DNA Damage and Apoptosis

Most cancer cells express high levels of telomerase and proliferate indefinitely. In addition to its telomere maintenance function, telomerase also has a pro-survival function resulting in an increased resistance against DNA damage and decreased apoptosis induction. However, the molecular mechanisms...

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Detalles Bibliográficos
Autores principales: Singhapol, Chatchawan, Pal, Deepali, Czapiewski, Rafal, Porika, Mahendar, Nelson, Glyn, Saretzki, Gabriele C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541395/
https://www.ncbi.nlm.nih.gov/pubmed/23326372
http://dx.doi.org/10.1371/journal.pone.0052989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541395/
https://www.ncbi.nlm.nih.gov/pubmed/23326372
http://dx.doi.org/10.1371/journal.pone.0052989

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