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Mitochondrial Telomerase Protects Cancer Cells from Nuclear DNA Damage and Apoptosis
Most cancer cells express high levels of telomerase and proliferate indefinitely. In addition to its telomere maintenance function, telomerase also has a pro-survival function resulting in an increased resistance against DNA damage and decreased apoptosis induction. However, the molecular mechanisms...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541395/ https://www.ncbi.nlm.nih.gov/pubmed/23326372 http://dx.doi.org/10.1371/journal.pone.0052989 |