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Down-Regulation of Protein Kinase Cδ Inhibits Inducible Nitric Oxide Synthase Expression through IRF1
In inflammation, pro-inflammatory cytokines and bacterial products induce the production of high amounts of NO by inducible nitric oxide synthase (iNOS) in inflammatory and tissue cells. NO is an effector molecule in innate immunity, and it also has regulatory and pro-inflammatory/destructive effect...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541401/ https://www.ncbi.nlm.nih.gov/pubmed/23326354 http://dx.doi.org/10.1371/journal.pone.0052741 |