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Down-Regulation of Protein Kinase Cδ Inhibits Inducible Nitric Oxide Synthase Expression through IRF1

In inflammation, pro-inflammatory cytokines and bacterial products induce the production of high amounts of NO by inducible nitric oxide synthase (iNOS) in inflammatory and tissue cells. NO is an effector molecule in innate immunity, and it also has regulatory and pro-inflammatory/destructive effect...

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Detalles Bibliográficos
Autores principales:	Leppänen, Tiina, Korhonen, Riku, Laavola, Mirka, Nieminen, Riina, Tuominen, Raimo K., Moilanen, Eeva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541401/ https://www.ncbi.nlm.nih.gov/pubmed/23326354 http://dx.doi.org/10.1371/journal.pone.0052741

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