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Sex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin

As discussed in the larger review in this special issue (MacDonald and Feifel), intranasal oxytocin (OT) is demonstrating a growing potential as a therapeutic agent in psychiatry. Importantly, research suggests that a variety of individual factors may influence a person’s response to OT. In this min...

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Detalles Bibliográficos
Autor principal: MacDonald, Kai S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541513/
https://www.ncbi.nlm.nih.gov/pubmed/23335876
http://dx.doi.org/10.3389/fnins.2012.00194
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author MacDonald, Kai S.
author_facet MacDonald, Kai S.
author_sort MacDonald, Kai S.
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description As discussed in the larger review in this special issue (MacDonald and Feifel), intranasal oxytocin (OT) is demonstrating a growing potential as a therapeutic agent in psychiatry. Importantly, research suggests that a variety of individual factors may influence a person’s response to OT. In this mini-review, I provide a review of three: (1) sex and hormonal status; (2) genetic variation in aspects of the OT system (i.e., OT receptors); and (3) attachment history. Each of these factors will be important to monitor as we strive to develop a richer understanding of OT’s role in human development, brain-based disease, and the potential for individualized, OT-targeted treatments.
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spelling pubmed-35415132013-01-18 Sex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin MacDonald, Kai S. Front Neurosci Neuroscience As discussed in the larger review in this special issue (MacDonald and Feifel), intranasal oxytocin (OT) is demonstrating a growing potential as a therapeutic agent in psychiatry. Importantly, research suggests that a variety of individual factors may influence a person’s response to OT. In this mini-review, I provide a review of three: (1) sex and hormonal status; (2) genetic variation in aspects of the OT system (i.e., OT receptors); and (3) attachment history. Each of these factors will be important to monitor as we strive to develop a richer understanding of OT’s role in human development, brain-based disease, and the potential for individualized, OT-targeted treatments. Frontiers Media S.A. 2013-01-10 /pmc/articles/PMC3541513/ /pubmed/23335876 http://dx.doi.org/10.3389/fnins.2012.00194 Text en Copyright © 2013 MacDonald. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.
spellingShingle Neuroscience
MacDonald, Kai S.
Sex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin
title Sex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin
title_full Sex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin
title_fullStr Sex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin
title_full_unstemmed Sex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin
title_short Sex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin
title_sort sex, receptors, and attachment: a review of individual factors influencing response to oxytocin
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541513/
https://www.ncbi.nlm.nih.gov/pubmed/23335876
http://dx.doi.org/10.3389/fnins.2012.00194
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