Cargando…
Sex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin
As discussed in the larger review in this special issue (MacDonald and Feifel), intranasal oxytocin (OT) is demonstrating a growing potential as a therapeutic agent in psychiatry. Importantly, research suggests that a variety of individual factors may influence a person’s response to OT. In this min...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541513/ https://www.ncbi.nlm.nih.gov/pubmed/23335876 http://dx.doi.org/10.3389/fnins.2012.00194 |
_version_ | 1782255369963175936 |
---|---|
author | MacDonald, Kai S. |
author_facet | MacDonald, Kai S. |
author_sort | MacDonald, Kai S. |
collection | PubMed |
description | As discussed in the larger review in this special issue (MacDonald and Feifel), intranasal oxytocin (OT) is demonstrating a growing potential as a therapeutic agent in psychiatry. Importantly, research suggests that a variety of individual factors may influence a person’s response to OT. In this mini-review, I provide a review of three: (1) sex and hormonal status; (2) genetic variation in aspects of the OT system (i.e., OT receptors); and (3) attachment history. Each of these factors will be important to monitor as we strive to develop a richer understanding of OT’s role in human development, brain-based disease, and the potential for individualized, OT-targeted treatments. |
format | Online Article Text |
id | pubmed-3541513 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-35415132013-01-18 Sex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin MacDonald, Kai S. Front Neurosci Neuroscience As discussed in the larger review in this special issue (MacDonald and Feifel), intranasal oxytocin (OT) is demonstrating a growing potential as a therapeutic agent in psychiatry. Importantly, research suggests that a variety of individual factors may influence a person’s response to OT. In this mini-review, I provide a review of three: (1) sex and hormonal status; (2) genetic variation in aspects of the OT system (i.e., OT receptors); and (3) attachment history. Each of these factors will be important to monitor as we strive to develop a richer understanding of OT’s role in human development, brain-based disease, and the potential for individualized, OT-targeted treatments. Frontiers Media S.A. 2013-01-10 /pmc/articles/PMC3541513/ /pubmed/23335876 http://dx.doi.org/10.3389/fnins.2012.00194 Text en Copyright © 2013 MacDonald. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc. |
spellingShingle | Neuroscience MacDonald, Kai S. Sex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin |
title | Sex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin |
title_full | Sex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin |
title_fullStr | Sex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin |
title_full_unstemmed | Sex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin |
title_short | Sex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin |
title_sort | sex, receptors, and attachment: a review of individual factors influencing response to oxytocin |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541513/ https://www.ncbi.nlm.nih.gov/pubmed/23335876 http://dx.doi.org/10.3389/fnins.2012.00194 |
work_keys_str_mv | AT macdonaldkais sexreceptorsandattachmentareviewofindividualfactorsinfluencingresponsetooxytocin |