Fatal Hepatocellular Carcinoma in a Patient with Occult Hepatitis B Virus Infection following the Administration of R-CHOP for Diffuse Large B-Cell Lymphoma

Occult hepatitis B (OBI) is caused by a persistent low-level replication of HBV. Like overt HBV infection, OBI can be associated with the integration of HBV sequences into the host genome and has a substantial clinical relevance for patients who are severely immunosuppressed for long durations. We p...

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Autores principales: Pitini, Vincenzo, Rizzo, Massimo, Arrigo, Carmela, Mondello, Patrizia, Altavilla, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541567/
https://www.ncbi.nlm.nih.gov/pubmed/23326737
http://dx.doi.org/10.1155/2012/803298
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author Pitini, Vincenzo
Rizzo, Massimo
Arrigo, Carmela
Mondello, Patrizia
Altavilla, Giuseppe
author_facet Pitini, Vincenzo
Rizzo, Massimo
Arrigo, Carmela
Mondello, Patrizia
Altavilla, Giuseppe
author_sort Pitini, Vincenzo
collection PubMed
description Occult hepatitis B (OBI) is caused by a persistent low-level replication of HBV. Like overt HBV infection, OBI can be associated with the integration of HBV sequences into the host genome and has a substantial clinical relevance for patients who are severely immunosuppressed for long durations. We present the case of a patient with a diffuse large B-cell non-Hodgkin lymphoma and OBI who developed a hepatocellular carcinoma with a fulminant clinical course following the administration of rituximab plus CHOP.
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spelling pubmed-35415672013-01-16 Fatal Hepatocellular Carcinoma in a Patient with Occult Hepatitis B Virus Infection following the Administration of R-CHOP for Diffuse Large B-Cell Lymphoma Pitini, Vincenzo Rizzo, Massimo Arrigo, Carmela Mondello, Patrizia Altavilla, Giuseppe Case Rep Hematol Case Report Occult hepatitis B (OBI) is caused by a persistent low-level replication of HBV. Like overt HBV infection, OBI can be associated with the integration of HBV sequences into the host genome and has a substantial clinical relevance for patients who are severely immunosuppressed for long durations. We present the case of a patient with a diffuse large B-cell non-Hodgkin lymphoma and OBI who developed a hepatocellular carcinoma with a fulminant clinical course following the administration of rituximab plus CHOP. Hindawi Publishing Corporation 2012 2012-12-26 /pmc/articles/PMC3541567/ /pubmed/23326737 http://dx.doi.org/10.1155/2012/803298 Text en Copyright © 2012 Vincenzo Pitini et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Pitini, Vincenzo
Rizzo, Massimo
Arrigo, Carmela
Mondello, Patrizia
Altavilla, Giuseppe
Fatal Hepatocellular Carcinoma in a Patient with Occult Hepatitis B Virus Infection following the Administration of R-CHOP for Diffuse Large B-Cell Lymphoma
title Fatal Hepatocellular Carcinoma in a Patient with Occult Hepatitis B Virus Infection following the Administration of R-CHOP for Diffuse Large B-Cell Lymphoma
title_full Fatal Hepatocellular Carcinoma in a Patient with Occult Hepatitis B Virus Infection following the Administration of R-CHOP for Diffuse Large B-Cell Lymphoma
title_fullStr Fatal Hepatocellular Carcinoma in a Patient with Occult Hepatitis B Virus Infection following the Administration of R-CHOP for Diffuse Large B-Cell Lymphoma
title_full_unstemmed Fatal Hepatocellular Carcinoma in a Patient with Occult Hepatitis B Virus Infection following the Administration of R-CHOP for Diffuse Large B-Cell Lymphoma
title_short Fatal Hepatocellular Carcinoma in a Patient with Occult Hepatitis B Virus Infection following the Administration of R-CHOP for Diffuse Large B-Cell Lymphoma
title_sort fatal hepatocellular carcinoma in a patient with occult hepatitis b virus infection following the administration of r-chop for diffuse large b-cell lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541567/
https://www.ncbi.nlm.nih.gov/pubmed/23326737
http://dx.doi.org/10.1155/2012/803298
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