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Influence of cancerostatic perifosine on membrane fluidity of liposomes and different cell lines as measured by electron paramagnetic resonance

AIM: To test whether membrane fluidity and its changes are important for the sensitivity of cells to the action of perifosine (OPP), a new anticancer drug targeting cell membrane and not DNA. METHOD: Influence of OPP on the membrane structure of OPP-resistant MCF7, and OPP-sensitive MT3 breast cance...

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Detalles Bibliográficos
Autores principales:	Podlipec, Rok, Koklic, Tilen, Štrancar, Janez, Mravljak, Janez, Šentjurc, Marjeta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Croatian Medical Schools 2012
Materias:	Medical Research in Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541582/ https://www.ncbi.nlm.nih.gov/pubmed/23275321 http://dx.doi.org/10.3325/cmj.2012.53.558

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