Leptin Locally Synthesized in Carotid Atherosclerotic Plaques Could Be Associated With Lesion Instability and Cerebral Emboli

BACKGROUND: Unstable carotid plaques cause cerebral emboli. Leptin promotes atherosclerosis and vessel wall remodeling. We hypothesized that carotid atherosclerotic lesion instability is associated with local leptin synthesis. METHODS AND RESULTS: Carotid endarterectomy plaques from symptomatic (n=4...

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Detalles Bibliográficos
Autores principales: Schneiderman, Jacob, Schaefer, Katrin, Kolodgie, Frank D., Savion, Naphtali, Kotev-Emeth, Shlomo, Dardik, Rima, Simon, Amos J., Halak, Moshe, Pariente, Clara, Engelberg, Isaac, Konstantinides, Stavros, Virmani, Renu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541612/
https://www.ncbi.nlm.nih.gov/pubmed/23316287
http://dx.doi.org/10.1161/JAHA.112.001727

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