A Case of Hypogonadotropic Hypogonadism Caused by Opioid Treatment for Nonmalignant Chronic Pain

We report a case of 42-year-old male patient with hypogonadotropic hypogonadism. He suffered from general fatigue and erectile dysfunction after the treatment with transdermal fentanyl for chronic pain by traffic injury. Endocrine examinations and hormone stimulating tests showed that he had hypogon...

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Autores principales: Tabuchi, Yukiko, Yasuda, Tetsuyuki, Kaneto, Hideaki, Kitamura, Tetsuhiro, Kozawa, Junji, Otsuki, Michio, Imagawa, Akihisa, Nakae, Aya, Matsuda, Youichi, Uematsu, Hironobu, Mashimo, Takashi, Shibata, Masahiko, Shimomura, Iichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541691/
https://www.ncbi.nlm.nih.gov/pubmed/23326276
http://dx.doi.org/10.1155/2012/740603
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author Tabuchi, Yukiko
Yasuda, Tetsuyuki
Kaneto, Hideaki
Kitamura, Tetsuhiro
Kozawa, Junji
Otsuki, Michio
Imagawa, Akihisa
Nakae, Aya
Matsuda, Youichi
Uematsu, Hironobu
Mashimo, Takashi
Shibata, Masahiko
Shimomura, Iichiro
author_facet Tabuchi, Yukiko
Yasuda, Tetsuyuki
Kaneto, Hideaki
Kitamura, Tetsuhiro
Kozawa, Junji
Otsuki, Michio
Imagawa, Akihisa
Nakae, Aya
Matsuda, Youichi
Uematsu, Hironobu
Mashimo, Takashi
Shibata, Masahiko
Shimomura, Iichiro
author_sort Tabuchi, Yukiko
collection PubMed
description We report a case of 42-year-old male patient with hypogonadotropic hypogonadism. He suffered from general fatigue and erectile dysfunction after the treatment with transdermal fentanyl for chronic pain by traffic injury. Endocrine examinations and hormone stimulating tests showed that he had hypogonadotropic hypogonadism. Brain magnetic resonance imaging (MRI) showed no abnormal findings, and he had no past history of accounting for acquired hypogonadotropic hypogonadism. Therefore, his hypogonadism was diagnosed to be caused by opioid treatment. Although opioid-induced endocrine dysfunctions are not widely recognized, this case suggests that we should consider the possibility of endocrine dysfunctions in patients with opioid treatment.
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spelling pubmed-35416912013-01-16 A Case of Hypogonadotropic Hypogonadism Caused by Opioid Treatment for Nonmalignant Chronic Pain Tabuchi, Yukiko Yasuda, Tetsuyuki Kaneto, Hideaki Kitamura, Tetsuhiro Kozawa, Junji Otsuki, Michio Imagawa, Akihisa Nakae, Aya Matsuda, Youichi Uematsu, Hironobu Mashimo, Takashi Shibata, Masahiko Shimomura, Iichiro Case Rep Med Case Report We report a case of 42-year-old male patient with hypogonadotropic hypogonadism. He suffered from general fatigue and erectile dysfunction after the treatment with transdermal fentanyl for chronic pain by traffic injury. Endocrine examinations and hormone stimulating tests showed that he had hypogonadotropic hypogonadism. Brain magnetic resonance imaging (MRI) showed no abnormal findings, and he had no past history of accounting for acquired hypogonadotropic hypogonadism. Therefore, his hypogonadism was diagnosed to be caused by opioid treatment. Although opioid-induced endocrine dysfunctions are not widely recognized, this case suggests that we should consider the possibility of endocrine dysfunctions in patients with opioid treatment. Hindawi Publishing Corporation 2012 2012-12-25 /pmc/articles/PMC3541691/ /pubmed/23326276 http://dx.doi.org/10.1155/2012/740603 Text en Copyright © 2012 Yukiko Tabuchi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tabuchi, Yukiko
Yasuda, Tetsuyuki
Kaneto, Hideaki
Kitamura, Tetsuhiro
Kozawa, Junji
Otsuki, Michio
Imagawa, Akihisa
Nakae, Aya
Matsuda, Youichi
Uematsu, Hironobu
Mashimo, Takashi
Shibata, Masahiko
Shimomura, Iichiro
A Case of Hypogonadotropic Hypogonadism Caused by Opioid Treatment for Nonmalignant Chronic Pain
title A Case of Hypogonadotropic Hypogonadism Caused by Opioid Treatment for Nonmalignant Chronic Pain
title_full A Case of Hypogonadotropic Hypogonadism Caused by Opioid Treatment for Nonmalignant Chronic Pain
title_fullStr A Case of Hypogonadotropic Hypogonadism Caused by Opioid Treatment for Nonmalignant Chronic Pain
title_full_unstemmed A Case of Hypogonadotropic Hypogonadism Caused by Opioid Treatment for Nonmalignant Chronic Pain
title_short A Case of Hypogonadotropic Hypogonadism Caused by Opioid Treatment for Nonmalignant Chronic Pain
title_sort case of hypogonadotropic hypogonadism caused by opioid treatment for nonmalignant chronic pain
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541691/
https://www.ncbi.nlm.nih.gov/pubmed/23326276
http://dx.doi.org/10.1155/2012/740603
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