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Controlled Human Malaria Infections by Intradermal Injection of Cryopreserved Plasmodium falciparum Sporozoites
Controlled human malaria infection with sporozoites is a standardized and powerful tool for evaluation of malaria vaccine and drug efficacy but so far only applied by exposure to bites of Plasmodium falciparum (Pf)-infected mosquitoes. We assessed in an open label Phase 1 trial, infection after intr...
Autores principales: | Roestenberg, Meta, Bijker, Else M., Sim, B. Kim Lee, Billingsley, Peter F., James, Eric R., Bastiaens, Guido J. H., Teirlinck, Anne C., Scholzen, Anja, Teelen, Karina, Arens, Theo, van der Ven, André J. A. M., Gunasekera, Anusha, Chakravarty, Sumana, Velmurugan, Soundarapandian, Hermsen, Cornelus C., Sauerwein, Robert W., Hoffman, Stephen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Tropical Medicine and Hygiene
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541746/ https://www.ncbi.nlm.nih.gov/pubmed/23149582 http://dx.doi.org/10.4269/ajtmh.2012.12-0613 |
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