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Specific Conformational States of Ras GTPase upon Effector Binding
[Image: see text] To uncover the structural and dynamical determinants involved in the highly specific binding of Ras GTPase to its effectors, the conformational states of Ras in uncomplexed form and complexed to the downstream effectors Byr2, PI3Kγ, PLCε, and RalGDS were investigated using molecula...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541755/ https://www.ncbi.nlm.nih.gov/pubmed/23316125 http://dx.doi.org/10.1021/ct3007265 |