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Vaccinia virus protein C4 inhibits NF-κB activation and promotes virus virulence

Vaccinia virus (VACV) strain Western Reserve protein C4 has been characterized and its function and contribution to virus virulence assessed. Bioinformatic analysis showed that C4 is conserved in six orthopoxvirus species and shares 43 % amino acid identity with VACV protein C16, a known virulence f...

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Detalles Bibliográficos
Autores principales:	Ember, Stuart W. J., Ren, Hongwei, Ferguson, Brian J., Smith, Geoffrey L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for General Microbiology 2012
Materias:	Animal
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541790/ https://www.ncbi.nlm.nih.gov/pubmed/22791606 http://dx.doi.org/10.1099/vir.0.045070-0

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