An investigation of herpes simplex virus promoter activity compatible with latency establishment reveals VP16-independent activation of immediate-early promoters in sensory neurones

Herpes simplex virus (HSV) type-1 establishes lifelong latency in sensory neurones and it is widely assumed that latency is the consequence of a failure to initiate virus immediate-early (IE) gene expression. However, using a Cre reporter mouse system in conjunction with Cre-expressing HSV-1 recombi...

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Detalles Bibliográficos
Autores principales: Proença, João T., Coleman, Heather M., Nicoll, Michael P., Connor, Viv, Preston, Christopher M., Arthur, Jane, Efstathiou, Stacey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2011
Materias:
Animal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541806/
https://www.ncbi.nlm.nih.gov/pubmed/21752961
http://dx.doi.org/10.1099/vir.0.034728-0

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