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Sipuleucel-T immune parameters correlate with survival: an analysis of the randomized phase 3 clinical trials in men with castration-resistant prostate cancer
PURPOSE: Sipuleucel-T, the first FDA-approved autologous cellular immunotherapy for treatment of advanced prostate cancer, is manufactured by activating peripheral blood mononuclear cells, including antigen presenting cells (APCs), with a fusion protein containing prostatic acid phosphatase. Analysi...
Autores principales: | Sheikh, Nadeem A., Petrylak, Daniel, Kantoff, Philip W., dela Rosa, Corazon, Stewart, Frances P., Kuan, Ling-Yu, Whitmore, James B., Trager, James B., Poehlein, Christian H., Frohlich, Mark W., Urdal, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541926/ https://www.ncbi.nlm.nih.gov/pubmed/22865266 http://dx.doi.org/10.1007/s00262-012-1317-2 |
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