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N-acetylation and phosphorylation of Sec complex subunits in the ER membrane

BACKGROUND: Covalent modifications of proteins provide a mechanism to control protein function. Here, we have investigated modifications of the heptameric Sec complex which is responsible for post-translational protein import into the endoplasmic reticulum (ER). It consists of the Sec61 complex (Sec...

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Detalles Bibliográficos
Autores principales: Soromani, Christina, Zeng, Naiyan, Hollemeyer, Klaus, Heinzle, Elmar, Klein, Marie-Christine, Tretter, Thomas, Seaman, Matthew N J, Römisch, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541991/
https://www.ncbi.nlm.nih.gov/pubmed/23237413
http://dx.doi.org/10.1186/1471-2121-13-34