Softwares and methods for estimating genetic ancestry in human populations

The estimation of genetic ancestry in human populations has important applications in medical genetic studies. Genetic ancestry is used to control for population stratification in genetic association studies, and is used to understand the genetic basis for ethnic differences in disease susceptibilit...

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Detalles Bibliográficos
Autores principales: Liu, Yushi, Nyunoya, Toru, Leng, Shuguang, Belinsky, Steven A, Tesfaigzi, Yohannes, Bruse, Shannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Software Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542037/
https://www.ncbi.nlm.nih.gov/pubmed/23289408
http://dx.doi.org/10.1186/1479-7364-7-1
Descripción
Sumario:The estimation of genetic ancestry in human populations has important applications in medical genetic studies. Genetic ancestry is used to control for population stratification in genetic association studies, and is used to understand the genetic basis for ethnic differences in disease susceptibility. In this review, we present an overview of genetic ancestry estimation in human disease studies, followed by a review of popular softwares and methods used for this estimation.

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