Softwares and methods for estimating genetic ancestry in human populations

The estimation of genetic ancestry in human populations has important applications in medical genetic studies. Genetic ancestry is used to control for population stratification in genetic association studies, and is used to understand the genetic basis for ethnic differences in disease susceptibilit...

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Detalles Bibliográficos
Autores principales: Liu, Yushi, Nyunoya, Toru, Leng, Shuguang, Belinsky, Steven A, Tesfaigzi, Yohannes, Bruse, Shannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Software Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542037/
https://www.ncbi.nlm.nih.gov/pubmed/23289408
http://dx.doi.org/10.1186/1479-7364-7-1
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author Liu, Yushi
Nyunoya, Toru
Leng, Shuguang
Belinsky, Steven A
Tesfaigzi, Yohannes
Bruse, Shannon
author_facet Liu, Yushi
Nyunoya, Toru
Leng, Shuguang
Belinsky, Steven A
Tesfaigzi, Yohannes
Bruse, Shannon
author_sort Liu, Yushi
collection PubMed
description The estimation of genetic ancestry in human populations has important applications in medical genetic studies. Genetic ancestry is used to control for population stratification in genetic association studies, and is used to understand the genetic basis for ethnic differences in disease susceptibility. In this review, we present an overview of genetic ancestry estimation in human disease studies, followed by a review of popular softwares and methods used for this estimation.
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spelling pubmed-35420372013-01-11 Softwares and methods for estimating genetic ancestry in human populations Liu, Yushi Nyunoya, Toru Leng, Shuguang Belinsky, Steven A Tesfaigzi, Yohannes Bruse, Shannon Hum Genomics Software Review The estimation of genetic ancestry in human populations has important applications in medical genetic studies. Genetic ancestry is used to control for population stratification in genetic association studies, and is used to understand the genetic basis for ethnic differences in disease susceptibility. In this review, we present an overview of genetic ancestry estimation in human disease studies, followed by a review of popular softwares and methods used for this estimation. BioMed Central 2013-01-05 /pmc/articles/PMC3542037/ /pubmed/23289408 http://dx.doi.org/10.1186/1479-7364-7-1 Text en Copyright ©2013 Liu et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Software Review
Liu, Yushi
Nyunoya, Toru
Leng, Shuguang
Belinsky, Steven A
Tesfaigzi, Yohannes
Bruse, Shannon
Softwares and methods for estimating genetic ancestry in human populations
title Softwares and methods for estimating genetic ancestry in human populations
title_full Softwares and methods for estimating genetic ancestry in human populations
title_fullStr Softwares and methods for estimating genetic ancestry in human populations
title_full_unstemmed Softwares and methods for estimating genetic ancestry in human populations
title_short Softwares and methods for estimating genetic ancestry in human populations
title_sort softwares and methods for estimating genetic ancestry in human populations
topic Software Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542037/
https://www.ncbi.nlm.nih.gov/pubmed/23289408
http://dx.doi.org/10.1186/1479-7364-7-1
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