Cargando…
A Drosophila Model of High Sugar Diet-Induced Cardiomyopathy
Diets high in carbohydrates have long been linked to progressive heart dysfunction, yet the mechanisms by which chronic high sugar leads to heart failure remain poorly understood. Here we combine diet, genetics, and physiology to establish an adult Drosophila melanogaster model of chronic high sugar...
Autores principales: | Na, Jianbo, Musselman, Laura Palanker, Pendse, Jay, Baranski, Thomas J., Bodmer, Rolf, Ocorr, Karen, Cagan, Ross |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542070/ https://www.ncbi.nlm.nih.gov/pubmed/23326243 http://dx.doi.org/10.1371/journal.pgen.1003175 |
Ejemplares similares
-
A high-sugar diet produces obesity and insulin resistance in wild-type Drosophila
por: Musselman, Laura Palanker, et al.
Publicado: (2011) -
SPARC–Dependent Cardiomyopathy in Drosophila
por: Hartley, Paul S., et al.
Publicado: (2016) -
Similar effects of high-fructose and high-glucose feeding in a Drosophila model of obesity and diabetes
por: Musselman, Laura Palanker, et al.
Publicado: (2019) -
A Drosophila functional evaluation of candidates from human genome-wide association studies of type 2 diabetes and related metabolic traits identifies tissue-specific roles for dHHEX
por: Pendse, Jay, et al.
Publicado: (2013) -
A Drosophila model linking diet-induced metabolic disease and cancer
por: Hirabayashi, Susumu, et al.
Publicado: (2014)