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Asymmetric PTEN Distribution Regulated by Spatial Heterogeneity in Membrane-Binding State Transitions
The molecular mechanisms that underlie asymmetric PTEN distribution at the posterior of polarized motile cells and regulate anterior pseudopod formation were addressed by novel single-molecule tracking analysis. Heterogeneity in the lateral mobility of PTEN on a membrane indicated the existence of t...
Autores principales: | Matsuoka, Satomi, Shibata, Tatsuo, Ueda, Masahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542079/ https://www.ncbi.nlm.nih.gov/pubmed/23326224 http://dx.doi.org/10.1371/journal.pcbi.1002862 |
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