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Aberration in DNA Methylation in B-Cell Lymphomas Has a Complex Origin and Increases with Disease Severity

Despite mounting evidence that epigenetic abnormalities play a key role in cancer biology, their contributions to the malignant phenotype remain poorly understood. Here we studied genome-wide DNA methylation in normal B-cell populations and subtypes of B-cell non-Hodgkin lymphoma: follicular lymphom...

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Detalles Bibliográficos
Autores principales: De, Subhajyoti, Shaknovich, Rita, Riester, Markus, Elemento, Olivier, Geng, Huimin, Kormaksson, Matthias, Jiang, Yanwen, Woolcock, Bruce, Johnson, Nathalie, Polo, Jose M., Cerchietti, Leandro, Gascoyne, Randy D., Melnick, Ari, Michor, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542081/
https://www.ncbi.nlm.nih.gov/pubmed/23326238
http://dx.doi.org/10.1371/journal.pgen.1003137