Cargando…
Ubiquinol decreases monocytic expression and DNA methylation of the pro-inflammatory chemokine ligand 2 gene in humans
BACKGROUND: Coenzyme Q(10) is an essential cofactor in the respiratory chain and serves in its reduced form, ubiquinol, as a potent antioxidant. Studies in vitro and in vivo provide evidence that ubiquinol reduces inflammatory processes via gene expression. Here we investigate the putative link betw...
Autores principales: | Fischer, Alexandra, Onur, Simone, Schmelzer, Constance, Döring, Frank |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542089/ https://www.ncbi.nlm.nih.gov/pubmed/23021568 http://dx.doi.org/10.1186/1756-0500-5-540 |
Ejemplares similares
-
Ubiquinol reduces gamma glutamyltransferase as a marker of oxidative stress in humans
por: Onur, Simone, et al.
Publicado: (2014) -
Ubiquinol affects the expression of genes involved in PPARα signalling and lipid metabolism without changes in methylation of CpG promoter islands in the liver of mice
por: Schmelzer, Constance, et al.
Publicado: (2012) -
Effects of Ubiquinol-10 on MicroRNA-146a Expression In Vitro and In Vivo
por: Schmelzer, Constance, et al.
Publicado: (2009) -
Paraoxonase 1 polymorphism Q192R affects the pro-inflammatory cytokine TNF-alpha in healthy males
por: Lüersen, Kai, et al.
Publicado: (2011) -
In Vitro Effects of the Reduced Form of Coenzyme Q(10) on Secretion Levels of TNF-α and Chemokines in Response to LPS in the Human Monocytic Cell Line THP-1
por: Schmelzer, Constance, et al.
Publicado: (2009)