Cargando…

Healthy goats naturally devoid of prion protein

Prion diseases such as scrapie in small ruminants, bovine spongiform encephalopathy (BSE) in cattle and Creutzfeldt-Jakob disease (CJD) in man, are fatal neurodegenerative disorders. These diseases result from the accumulation of misfolded conformers of the host-encoded prion protein (PrP) in the ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Benestad, Sylvie L, Austbø, Lars, Tranulis, Michael A, Espenes, Arild, Olsaker, Ingrid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542104/ https://www.ncbi.nlm.nih.gov/pubmed/23249298 http://dx.doi.org/10.1186/1297-9716-43-87

Ejemplares similares

Hematological shift in goat kids naturally devoid of prion protein
por: Reiten, Malin R., et al.
Publicado: (2015)

Goats naturally devoid of PrP(C) are resistant to scrapie
por: Salvesen, Øyvind, et al.
Publicado: (2020)

Prion protein in myelin maintenance: what does the goat say?
por: Skedsmo, Fredrik S., et al.
Publicado: (2020)

No evidence of uptake or propagation of reindeer CWD prions in environmentally exposed sheep
por: Harpaz, Erez, et al.
Publicado: (2022)

Goats without Prion Protein Display Enhanced Proinflammatory Pulmonary Signaling and Extracellular Matrix Remodeling upon Systemic Lipopolysaccharide Challenge
por: Salvesen, Øyvind, et al.
Publicado: (2017)

The Cellular Prion Protein: A Player in Immunological Quiescence
por: Bakkebø, Maren K., et al.
Publicado: (2015)

Phenotypic characterization of cells participating in transport of prion protein aggregates across the intestinal mucosa of sheep
por: Piercey Åkesson, Caroline, et al.
Publicado: (2012)

Inter- and intra-species conversion efficacies of Norwegian prion isolates estimated by serial protein misfolding cyclic amplification
por: Harpaz, Erez, et al.
Publicado: (2023)

Loss of prion protein induces a primed state of type I interferon-responsive genes
por: Malachin, Giulia, et al.
Publicado: (2017)

LPS-induced systemic inflammation reveals an immunomodulatory role for the prion protein at the blood-brain interface
por: Salvesen, Ø., et al.
Publicado: (2017)

Biological and Biochemical Characterization of Mice Expressing Prion Protein Devoid of the Octapeptide Repeat Region after Infection with Prions
por: Yamaguchi, Yoshitaka, et al.
Publicado: (2012)

PrP Expression, PrP(Sc) Accumulation and Innervation of Splenic Compartments in Sheep Experimentally Infected with Scrapie
por: Sørby, Randi, et al.
Publicado: (2009)

Porcine Prion Protein as a Paradigm of Limited Susceptibility to Prion Strain Propagation
por: Espinosa, Juan Carlos, et al.
Publicado: (2020)

Prion potentiation after life-long dormancy in mice devoid of PrP
por: Martin, Davy, et al.
Publicado: (2021)

Chronic wasting disease associated with prion protein gene (PRNP) variation in Norwegian wild reindeer (Rangifer tarandus)
por: Güere, Mariella E., et al.
Publicado: (2019)

Neil3 induced neurogenesis protects against prion disease during the clinical phase
por: Jalland, Clara M. O., et al.
Publicado: (2016)

Stress Resilience of Spermatozoa and Blood Mononuclear Cells without Prion Protein
por: Reiten, Malin R., et al.
Publicado: (2018)

Identification of differentially expressed genes in ileal Peyer's Patch of scrapie-infected sheep using RNA arbitrarily primed PCR
por: Austbø, Lars, et al.
Publicado: (2008)

Whole genome sequencing of 51 breast cancers reveals that tumors are devoid of bovine leukemia virus DNA
por: Gillet, Nicolas A., et al.
Publicado: (2016)

Propagation of RML Prions in Mice Expressing PrP Devoid of GPI Anchor Leads to Formation of a Novel, Stable Prion Strain
por: Mahal, Sukhvir Paul, et al.
Publicado: (2012)

Erratum to: Porcine Prion Protein as a Paradigm of Limited Susceptibility to Prion Strain Propagation
por: Espinosa, Juan Carlos, et al.
Publicado: (2020)

Cell and context-dependent sorting of neuropathy-associated protein NDRG1 – insights from canine tissues and primary Schwann cell cultures
por: Skedsmo, Fredrik S., et al.
Publicado: (2019)

Mouse-Hamster Chimeric Prion Protein (PrP) Devoid of N-Terminal Residues 23-88 Restores Susceptibility to 22L Prions, but Not to RML Prions in PrP-Knockout Mice
por: Uchiyama, Keiji, et al.
Publicado: (2014)

Ultraviolet-ozone treatment reduces levels of disease-associated prion protein and prion infectivity
por: Johnson, Christopher J, et al.
Publicado: (2009)

Peroxiredoxin 6 promotes upregulation of the prion protein (PrP) in neuronal cells of prion-infected mice
por: Wagner, Wibke, et al.
Publicado: (2012)

Transcription of reference genes used for quantitative RT-PCR in Atlantic salmon is affected by viral infection
por: Løvoll, Marie, et al.
Publicado: (2011)

Activation of innate immune genes in caprine blood leukocytes after systemic endotoxin challenge
por: Salvesen, Øyvind, et al.
Publicado: (2016)

Ablation of prion protein immunoreactivity by heating in saturated calcium hydroxide
por: Greenlee, Justin J, et al.
Publicado: (2008)

Characterization of goat prions demonstrates geographical variation of scrapie strains in Europe and reveals the composite nature of prion strains
por: Nonno, Romolo, et al.
Publicado: (2020)

Production of 2-ketoisocaproate with Corynebacterium glutamicum strains devoid of plasmids and heterologous genes
por: Vogt, Michael, et al.
Publicado: (2015)

First case of chronic wasting disease in Europe in a Norwegian free-ranging reindeer
por: Benestad, Sylvie L., et al.
Publicado: (2016)

Prions in Milk from Ewes Incubating Natural Scrapie
por: Lacroux, Caroline, et al.
Publicado: (2008)

Genetic variability of the prion protein gene in Indonesian goat breeds
por: Pakpahan, Suhendra, et al.
Publicado: (2023)

Similar Biochemical Signatures and Prion Protein Genotypes in Atypical Scrapie and Nor98 Cases, France and Norway
por: Arsac, Jean-Noël, et al.
Publicado: (2007)

Differential modulation of NMDA and AMPA receptors by cellular prion protein and copper ions
por: Huang, Sun, et al.
Publicado: (2018)

Pathological pigmentation in cardiac tissues of Atlantic salmon (Salmo salar L.) with cardiomyopathy syndrome
por: Fagerland, Hilde AS, et al.
Publicado: (2013)

The Diverse Calpain Family in Trypanosomatidae: Functional Proteins Devoid of Proteolytic Activity?
por: Ennes-Vidal, Vítor, et al.
Publicado: (2021)

Are Human Digit Muscles Devoid of Recurrent Inhibition?
por: Piotrkiewicz, Maria, et al.
Publicado: (2016)

The prion protein regulates beta-amyloid-mediated self-renewal of neural stem cells in vitro
por: Collins, Steven J, et al.
Publicado: (2015)

PRNP genetic variability and molecular typing of natural goat scrapie isolates in a high number of infected flocks
por: Fragkiadaki, Eirini G, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_mmsdoj14cq932bloj8ten2e5fk