Cargando…

Aqp5 Is a New Transcriptional Target of Dot1a and a Regulator of Aqp2

Dot1l encodes histone H3 K79 methyltransferase Dot1a. Mice with Dot1l deficiency in renal Aqp2-expressing cells (Dot1l(AC)) develop polyuria by unknown mechanisms. Here, we report that Aqp5 links Dot1l deletion to polyuria through Aqp2. cDNA array analysis revealed and real-time RT-qPCR validated Aq...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Hongyu, Chen, Lihe, Zhang, Xi, Zhou, Qiaoling, Li, Ju-Mei, Berger, Stefan, Borok, Zea, Zhou, Beiyun, Xiao, Zhou, Yin, Hongling, Liu, Mingyao, Wang, Ying, Jin, Jianping, Blackburn, Michael R., Xia, Yang, Zhang, Wenzheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542343/ https://www.ncbi.nlm.nih.gov/pubmed/23326416 http://dx.doi.org/10.1371/journal.pone.0053342

Ejemplares similares

Cell-specific expression of aquaporin-5 (Aqp5) in alveolar epithelium is directed by GATA6/Sp1 via histone acetylation
por: Flodby, Per, et al.
Publicado: (2017)

Immunohistochemical Localization of the Aquaporins AQP1, AQP3, AQP4, and AQP5 in the Mouse Respiratory System
por: Matsuzaki, Toshiyuki, et al.
Publicado: (2009)

AF17 Facilitates Dot1a Nuclear Export and Upregulates ENaC-Mediated Na+ Transport in Renal Collecting Duct Cells
por: Wu, Hongyu, et al.
Publicado: (2011)

AQP1 and AQP4 Contribution to Cerebrospinal Fluid Homeostasis
por: Trillo-Contreras, José Luis, et al.
Publicado: (2019)

Vitamin D Regulates the Expressions of AQP-1 and AQP-4 in Mice Kidneys
por: Fu, Yu, et al.
Publicado: (2019)

AQP5-1364A/C Polymorphism Affects AQP5 Promoter Methylation
por: Rump, Katharina, et al.
Publicado: (2022)

Expression of AQP5 and AQP8 in human colorectal carcinoma and their clinical significance
por: Wang, Wei, et al.
Publicado: (2012)

AQP3 and AQP5—Potential Regulators of Redox Status in Breast Cancer
por: Milković, Lidija, et al.
Publicado: (2021)

Immunohistochemical Localization of the Water Channels AQP4 and AQP5 in the Rat Pituitary Gland
por: Matsuzaki, Toshiyuki, et al.
Publicado: (2011)

AQP2 Plasma Membrane Diffusion Is Altered by the Degree of AQP2-S256 Phosphorylation
por: Arnspang, Eva C., et al.
Publicado: (2016)

Changes in the Expression of AQP4 and AQP9 in the Hippocampus Following Eclampsia-Like Seizure
por: Han, Xinjia, et al.
Publicado: (2018)

The pathogenesis of idiopathic normal pressure hydrocephalus based on the understanding of AQP1 and AQP4
por: Zhao, Zitong, et al.
Publicado: (2022)

Hydropenia may accelerates the progression of orthotopic bladder cancer induced by N-methyl-N-nitrosourea by increasing the expression levels of AQP1, AQP3, and AQP4
por: Pan, Jun-Wei, et al.
Publicado: (2021)

Expression and Significance of AQP3 in Cutaneous Lesions
por: Niu, Dongfeng, et al.
Publicado: (2021)

Differential Expression and Localization of Branchial AQP1 and AQP3 in Japanese Medaka (Oryzias latipes)
por: Ellis, Laura V., et al.
Publicado: (2019)

Unexpected localization of AQP3 and AQP4 induced by migration of primary cultured IMCD cells
por: Rose, Ralph, et al.
Publicado: (2021)

Differences in the localization of AQP1 and expression patterns of AQP isoforms in rat and mouse sciatic nerve and changes in rat AQPs expression after nerve crush injury
por: Segura-Anaya, Edith, et al.
Publicado: (2021)

Effects of Qutanhuoxue Decoction on AQP7 and AQP9 Expression in Nonalcoholic Fatty Liver Model Rats
por: Zheng, Ding, et al.
Publicado: (2019)

Expression Profiles of AQP3 and AQP4 in Lung Adenocarcinoma Samples Generated via Bronchoscopic Biopsies
por: Jaskiewicz, Lukasz, et al.
Publicado: (2022)

AQP1 in the Gastrointestinal Tract of Mice: Expression Pattern and Impact of AQP1 Knockout on Colonic Function
por: Volkart, Stefanie, et al.
Publicado: (2023)

Tissue Distribution of the Readthrough Isoform of AQP4 Reveals a Dual Role of AQP4ex Limited to CNS
por: Palazzo, Claudia, et al.
Publicado: (2020)

Neuroimmunological Implications of AQP4 in Astrocytes
por: Ikeshima-Kataoka, Hiroko
Publicado: (2016)

The effect of the interaction between aquaporin 0 (AQP0) and the filensin tail region on AQP0 water permeability
por: Nakazawa, Yosuke, et al.
Publicado: (2011)

Increased Expression of AQP 1 and AQP 5 in Rat Lungs Ventilated with Low Tidal Volume is Time Dependent
por: Fabregat, Gustavo, et al.
Publicado: (2014)

AQP4ex is crucial for the anchoring of AQP4 at the astrocyte end-feet and for neuromyelitis optica antibody binding
por: Palazzo, Claudia, et al.
Publicado: (2019)

Intrathrombotic appearances of AQP-1 and AQP-3 in relation to thrombus age in murine deep vein thrombosis model
por: Nosaka, Mizuho, et al.
Publicado: (2021)

Alteration of the translational readthrough isoform AQP4ex induces redistribution and downregulation of AQP4 in human glioblastoma
por: Valente, Onofrio, et al.
Publicado: (2022)

MiR-877 suppresses gastric cancer progression by downregulating AQP3
por: Zhu, Hongyu, et al.
Publicado: (2020)

Prolonged Starvation Causes Up-Regulation of AQP1 in Adipose Tissue Capillaries of AQP7 Knock-Out Mice
por: Skowronski, Mariusz T., et al.
Publicado: (2016)

Maternal Protein Restriction Differentially Alters the Expression of AQP1, AQP9 and VEGFr-2 in the Epididymis of Rat Offspring
por: Cavariani, Marilia Martins, et al.
Publicado: (2019)

Indirect Role of AQP4b and AQP4d Isoforms in Dynamics of Astrocyte Volume and Orthogonal Arrays of Particles
por: Lisjak, Marjeta, et al.
Publicado: (2020)

Reduced urinary release of AQP1‐ and AQP2‐bearing extracellular vesicles in patients with advanced chronic kidney disease
por: Oshikawa‐Hori, Sayaka, et al.
Publicado: (2021)

Unraveling Human AQP5-PIP Molecular Interaction and Effect on AQP5 Salivary Glands Localization in SS Patients
por: Chivasso, Clara, et al.
Publicado: (2021)

Aqp 9 and Brain Tumour Stem Cells
por: Fossdal, Guri, et al.
Publicado: (2012)

Regulation of AQP4 in the Central Nervous System
por: Vandebroek, Arno, et al.
Publicado: (2020)

Emerging roles for AQP in mammalian extracellular vesicles
por: Clarke-Bland, Charlotte E., et al.
Publicado: (2022)

Tanshinone IIA changed the amniotic fluid volume and regulated expression of AQP1 and AQP3 in amniotic epithelium cells: a promising drug treating abnormal amniotic fluid volume
por: Pan, Shuangjia, et al.
Publicado: (2023)

AQP2: Mutations Associated with Congenital Nephrogenic Diabetes Insipidus and Regulation by Post-Translational Modifications and Protein-Protein Interactions
por: Gao, Chao, et al.
Publicado: (2020)

AQP5 Is a Novel Prognostic Biomarker in Pancreatic Adenocarcinoma
por: Chen, Guo, et al.
Publicado: (2022)

Disruption of Membranes of Extracellular Vesicles Is Necessary for ELISA Determination of Urine AQP2: Proof of Disruption and Epitopes of AQP2 Antibodies
por: Nameta, Masaaki, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_p29e5v215u1ecq0lqb7d4jsbs4