Cargando…

Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease

Biomarkers are increasingly important in the clinical management of complex diseases, yet our ability to discover new biomarkers remains limited by our dependence on endogenous molecules. Here we describe the development of exogenously administered `synthetic biomarkers' composed of mass-encode...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kwong, Gabriel A., von Maltzahn, Geoffrey, Murugappan, Gayathree, Abudayyeh, Omar, Mo, Steven, Papayannopoulos, Ioannis A., Sverdlov, Deanna Y., Liu, Susan B., Warren, Andrew D., Popov, Yury, Schuppan, Detlef, Bhatia, Sangeeta N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542405/ https://www.ncbi.nlm.nih.gov/pubmed/23242163 http://dx.doi.org/10.1038/nbt.2464

Ejemplares similares

Broad-Spectrum Matrix Metalloproteinase Inhibition Curbs Inflammation and Liver Injury but Aggravates Experimental Liver Fibrosis in Mice
por: de Meijer, Vincent E., et al.
Publicado: (2010)

Nanoparticles That Sense Thrombin Activity As Synthetic Urinary Biomarkers of Thrombosis
por: Lin, Kevin Y., et al.
Publicado: (2013)

Selective targeting of lysyl oxidase-like 2 (LOXL2) suppresses hepatic fibrosis progression and accelerates its reversal
por: Ikenaga, Naoki, et al.
Publicado: (2017)

Disease Detection by Ultrasensitive Quantification of Microdosed Synthetic Urinary Biomarkers
por: Warren, Andrew D., et al.
Publicado: (2014)

Antimullerian hormone is a predictor of live birth in patients with recurrent pregnancy loss
por: Murugappan, Gayathree, et al.
Publicado: (2019)

Time to next pregnancy in spontaneous pregnancies versus treatment cycles in fertile patients with recurrent pregnancy loss
por: Perfetto, Candice O, et al.
Publicado: (2015)

Synthetic MRI, multiplexed sensitivity encoding, and BI-RADS for benign and malignant breast cancer discrimination
por: Liu, Jinrui, et al.
Publicado: (2023)

A New Synthetic Curcuminoid Displays Antitumor Activities in Metastasized Melanoma
por: Kaps, Leonard, et al.
Publicado: (2023)

Comparison of murine steatohepatitis models identifies a dietary intervention with robust fibrosis, ductular reaction, and rapid progression to cirrhosis and cancer
por: Wei, Guangyan, et al.
Publicado: (2020)

Assessment of patients’ perceptions towards embryo disposition after donation of embryos to a research biobank
por: Khorshid, Arian, et al.
Publicado: (2022)

Nanoparticle amplification via photothermal unveiling of cryptic collagen binding sites
por: Lo, Justin H., et al.
Publicado: (2013)

3D analysis of microvasculature in murine liver fibrosis models using synchrotron radiation-based microtomography
por: Wagner, Willi L., et al.
Publicado: (2020)

Encoding information in synthetic metabolomes
por: Kennedy, Eamonn, et al.
Publicado: (2019)

Coeliac Disease – New Pathophysiological Findings and Their Implications for Therapy
por: Stein, Jürgen, et al.
Publicado: (2014)

Targeting Cancer Associated Fibroblasts in Liver Fibrosis and Liver Cancer Using Nanocarriers
por: Kaps, Leonard, et al.
Publicado: (2020)

High-Multiplex Aptamer-Based Serum Proteomics to Identify Candidate Serum Biomarkers of Oral Squamous Cell Carcinoma
por: Blatt, Sebastian, et al.
Publicado: (2023)

Synchrony-Division Neural Multiplexing: An Encoding Model
por: Rezaei, Mohammad R., et al.
Publicado: (2023)

CRISPR-Cas-amplified urinary biomarkers for multiplexed and portable cancer diagnostics
por: Hao, Liangliang, et al.
Publicado: (2023)

Recognition-Encoded Synthetic Information Molecules
por: Iadevaia, Giulia, et al.
Publicado: (2023)

Multiplexed Sequence Encoding: A Framework for DNA Communication
por: Zakeri, Bijan, et al.
Publicado: (2016)

Multiplexed Continuous Biosensing by Single-Molecule Encoded Nanoswitches
por: Lubken, Rafiq M., et al.
Publicado: (2020)

Hydroxyproline-containing collagen analogs trigger the release and activation of collagen-sequestered proMMP-2 by competition with prodomain-derived peptide P(33-42)
por: Ruehl, Martin, et al.
Publicado: (2011)

Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis
por: An, Ping, et al.
Publicado: (2020)

The impact of estradiol on pregnancy outcomes in letrozole-stimulated frozen embryo transfer cycles
por: Zhang, Wendy Y., et al.
Publicado: (2021)

Phosphate Groups in the Lipid A Moiety Determine the Effects of LPS on Hepatic Stellate Cells: A Role for LPS-Dephosphorylating Activity in Liver Fibrosis
por: Schippers, Marlies, et al.
Publicado: (2020)

Digital multiplex ligation assay for highly multiplexed screening of β-lactamase-encoding genes in bacterial isolates
por: Tamminen, Manu, et al.
Publicado: (2020)

Wavelength-encoded laser particles for massively multiplexed cell tagging
por: Martino, Nicola, et al.
Publicado: (2019)

Synthetic extracellular matrices with function-encoding peptides
por: Ligorio, Cosimo, et al.
Publicado: (2023)

Celiac Disease and Glandular Autoimmunity
por: Kahaly, George J., et al.
Publicado: (2018)

Multiplexed Gene Expression Tuning with Orthogonal Synthetic Gene Circuits
por: Szenk, Mariola, et al.
Publicado: (2020)

Nano-Enhanced Cancer Immunotherapy: Immunology Encounters Nanotechnology
por: Bockamp, Ernesto, et al.
Publicado: (2020)

Reply to Comment on Huang, X., et al. “Sourdough Fermentation Degrades Wheat Alpha-Amylase/Trypsin Inhibitor (ATI) and Reduces Pro-Inflammatory Activity”. Foods 2020, 9, 943
por: Huang, Xin, et al.
Publicado: (2020)

Multiplex PCR for Rapid Detection of Genes Encoding Class A Carbapenemases
por: Hong, Sang Sook, et al.
Publicado: (2012)

Programming Nanopore Ion Flow for Encoded Multiplex MicroRNA Detection
por: Zhang, Xinyue, et al.
Publicado: (2014)

Fluorescence-Based Multiplex Protein Detection Using Optically Encoded Microbeads
por: Jun, Bong-Hyun, et al.
Publicado: (2012)

Upconversion Nanoparticles-Encoded Hydrogel Microbeads-Based Multiplexed Protein Detection
por: Shikha, Swati, et al.
Publicado: (2017)

Encoded metal nanoparticle-based molecular beacons for multiplexed detection of DNA
por: Sha, Michael Y., et al.
Publicado: (2005)

Encoding and Multiplexing Information Signals in Magnetic Multilayers with Fractional Skyrmion Tubes
por: Chen, Runze, et al.
Publicado: (2023)

Live-Cell Fluorescence Lifetime Multiplexing Using Synthetic Fluorescent Probes
por: Frei, Michelle S., et al.
Publicado: (2022)

Gut–CNS-Axis as Possibility to Modulate Inflammatory Disease Activity—Implications for Multiple Sclerosis
por: Fleck, Ann-Katrin, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_tpnoipnu216f9pkmam0m531o43