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Rac1 is required for Prkar1a-mediated Nf2 suppression in Schwann cell tumors

Schwannomas are peripheral nerve sheath tumors that often occur in the setting of an inherited tumor predisposition syndrome, including Neurofibromatosis Types 1 (NF1) and 2 (NF2), Familial Schwannomatosis (FS) and Carney Complex (CNC). Loss of the NF2 tumor suppressor (encoding NF2, or Merlin) is a...

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Detalles Bibliográficos
Autores principales:	Manchanda, Parmeet K., Jones, Georgette N., Lee, Audrey A., Pringle, Daphne R., Zhang, Mei, Yu, Lianbo, La Perle, Krista M. D., Kirschner, Lawrence S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542412/ https://www.ncbi.nlm.nih.gov/pubmed/23045281 http://dx.doi.org/10.1038/onc.2012.374

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