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Functional Insights from the Crystal Structure of the N-Terminal Domain of the Prototypical Toll Receptor

Drosophila melanogaster Toll is the founding member of an important family of pathogen-recognition receptors in humans, the Toll-like receptor (TLR) family. In contrast, the prototypical receptor is a cytokine-like receptor for Spätzle (Spz) protein and plays a dual role in both development and immu...

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Detalles Bibliográficos
Autores principales:	Gangloff, Monique, Arnot, Christopher J., Lewis, Miranda, Gay, Nicholas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542428/ https://www.ncbi.nlm.nih.gov/pubmed/23245851 http://dx.doi.org/10.1016/j.str.2012.11.003

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