CSN5 specifically interacts with CDK2 and controls senescence in a cytoplasmic cyclin E-mediated manner

The fifth component (CSN5) of the mammalian COP9 signalosome complex plays an essential role in cell proliferation and senescence, but its molecular mediator remains to be determined. Here, we searched for interactors among various cell cycle regulators, and found that CSN5, but not the CSN holo-com...

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Detalles Bibliográficos
Autores principales: Yoshida, Akihiro, Yoneda-Kato, Noriko, Kato, Jun-ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542532/
https://www.ncbi.nlm.nih.gov/pubmed/23316279
http://dx.doi.org/10.1038/srep01054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542532/
https://www.ncbi.nlm.nih.gov/pubmed/23316279
http://dx.doi.org/10.1038/srep01054

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