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CSN5 specifically interacts with CDK2 and controls senescence in a cytoplasmic cyclin E-mediated manner
The fifth component (CSN5) of the mammalian COP9 signalosome complex plays an essential role in cell proliferation and senescence, but its molecular mediator remains to be determined. Here, we searched for interactors among various cell cycle regulators, and found that CSN5, but not the CSN holo-com...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542532/ https://www.ncbi.nlm.nih.gov/pubmed/23316279 http://dx.doi.org/10.1038/srep01054 |