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Birth-and-Death of KLK3 and KLK2 in Primates: Evolution Driven by Reproductive Biology
The kallikrein (KLK) gene family comprises the largest uninterrupted locus of serine proteases in the human genome and represents a notable case for studying the evolutionary fate of duplicated genes. In primates, a recent duplication event gave rise to KLK2 and KLK3, both encoding essential protein...
Autores principales: | Marques, Patrícia Isabel, Bernardino, Rui, Fernandes, Teresa, Green, Eric D., Hurle, Belen, Quesada, Victor, Seixas, Susana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542562/ https://www.ncbi.nlm.nih.gov/pubmed/23204305 http://dx.doi.org/10.1093/gbe/evs111 |
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