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A Tight Link between Orthologs and Bidirectional Best Hits in Bacterial and Archaeal Genomes

Orthologous relationships between genes are routinely inferred from bidirectional best hits (BBH) in pairwise genome comparisons. However, to our knowledge, it has never been quantitatively demonstrated that orthologs form BBH. To test this “BBH-orthology conjecture,” we take advantage of the operon...

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Detalles Bibliográficos
Autores principales:	Wolf, Yuri I., Koonin, Eugene V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542571/ https://www.ncbi.nlm.nih.gov/pubmed/23160176 http://dx.doi.org/10.1093/gbe/evs100

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