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Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis

BACKGROUND: It is known that amyloid-β peptide (Aβ) plays a pivotal role in the pathogenesis of Alzheimer's disease (AD). Interaction between Aβ and the receptor for advanced glycation end products (RAGE) has been implicated in neuronal degeneration associated with this disease. Pinocembrin, a...

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Detalles Bibliográficos
Autores principales:	Liu, Rui, Wu, Cai-xia, Zhou, Dan, Yang, Fan, Tian, Shuo, Zhang, Li, Zhang, Tian-tai, Du, Guan-hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542580/ https://www.ncbi.nlm.nih.gov/pubmed/22989295 http://dx.doi.org/10.1186/1741-7015-10-105

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