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Estimating the Rate of Irreversibility in Protein Evolution
Whether or not evolutionary change is inherently irreversible remains a controversial topic. Some examples of evolutionary irreversibility are known; however, this question has not been comprehensively addressed at the molecular level. Here, we use data from 221 human genes with known pathogenic mut...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542581/ https://www.ncbi.nlm.nih.gov/pubmed/23132897 http://dx.doi.org/10.1093/gbe/evs096 |