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Dnmt1-dependent DNA methylation is essential for photoreceptor terminal differentiation and retinal neuron survival

Epigenetic regulation of the genome is critical for the emergence of diverse cell lineages during development. To understand the role of DNA methylation during retinal network formation, we generated a mouse retinal-specific Dnmt1 deletion mutation from the onset of neurogenesis. In the hypomethylat...

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Detalles Bibliográficos
Autores principales:	Rhee, K-D, Yu, J, Zhao, C Y, Fan, G, Yang, X-J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542601/ https://www.ncbi.nlm.nih.gov/pubmed/23171847 http://dx.doi.org/10.1038/cddis.2012.165

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