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Dysregulation of core components of SCF complex in poly-glutamine disorders

Poly-glutamine (polyQ) diseases are neurodegenerative disorders characterised by expanded CAG repeats in the causative genes whose proteins form inclusion bodies. Various E3 ubiquitin ligases are implicated in neurodegenerative disorders. We report that dysfunction of the SCF (Skp1-Cul1-F-box protei...

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Detalles Bibliográficos
Autores principales:	Bhutani, S, Das, A, Maheshwari, M, Lakhotia, S C, Jana, N R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542602/ https://www.ncbi.nlm.nih.gov/pubmed/23171848 http://dx.doi.org/10.1038/cddis.2012.166

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