JNK2 is activated during ER stress and promotes cell survival

Adaptation to endoplasmic reticulum (ER) stress relies on activation of the unfolded protein response (UPR) and induction of autophagy. Indeed, cells die if ER stress is not countered by the UPR. Here we show in U937 cells that the ER stressors tunicamycin and thapsigargin cause increased expression...

Descripción completa

Detalles Bibliográficos
Autores principales: Raciti, M, Lotti, L V, Valia, S, Pulcinelli, F M, Di Renzo, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542603/
https://www.ncbi.nlm.nih.gov/pubmed/23171849
http://dx.doi.org/10.1038/cddis.2012.167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542603/
https://www.ncbi.nlm.nih.gov/pubmed/23171849
http://dx.doi.org/10.1038/cddis.2012.167

Ejemplares similares