miR-29b sensitizes multiple myeloma cells to bortezomib-induced apoptosis through the activation of a feedback loop with the transcription factor Sp1

MicroRNAs (miRNAs) with tumor-suppressor potential might have therapeutic applications in multiple myeloma (MM) through the modulation of still undiscovered molecular pathways. Here, we investigated the effects of enforced expression of miR-29b on the apoptotic occurrence in MM and highlighted its r...

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Detalles Bibliográficos
Autores principales: Amodio, N, Di Martino, M T, Foresta, U, Leone, E, Lionetti, M, Leotta, M, Gullà, A M, Pitari, M R, Conforti, F, Rossi, M, Agosti, V, Fulciniti, M, Misso, G, Morabito, F, Ferrarini, M, Neri, A, Caraglia, M, Munshi, N C, Anderson, K C, Tagliaferri, P, Tassone, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542610/
https://www.ncbi.nlm.nih.gov/pubmed/23190608
http://dx.doi.org/10.1038/cddis.2012.175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542610/
https://www.ncbi.nlm.nih.gov/pubmed/23190608
http://dx.doi.org/10.1038/cddis.2012.175

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