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PRAP1 is a novel executor of p53-dependent mechanisms in cell survival after DNA damage
p53 has a crucial role in governing cellular mechanisms in response to a broad range of genotoxic stresses. During DNA damage, p53 can either promote cell survival by activating senescence or cell-cycle arrest and DNA repair to maintain genomic integrity for cell survival or direct cells to undergo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542616/ https://www.ncbi.nlm.nih.gov/pubmed/23235459 http://dx.doi.org/10.1038/cddis.2012.180 |