Functional cooperativity by direct interaction between PAK4 and MMP-2 in the regulation of anoikis resistance, migration and invasion in glioma

Gliomas display anoikis resistance, enhanced invasion in to the adjacent brain parenchyma and eventually recur despite using the standard therapies. Our studies on increased anoikis sensitization in matrix metalloproteinase-2 (MMP-2)-knockdown 4910 and 5310 human glioma xenograft cells were interest...

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Detalles Bibliográficos
Autores principales: Kesanakurti, D, Chetty, C, Rajasekhar Maddirela, D, Gujrati, M, Rao, J S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542618/
https://www.ncbi.nlm.nih.gov/pubmed/23254288
http://dx.doi.org/10.1038/cddis.2012.182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542618/
https://www.ncbi.nlm.nih.gov/pubmed/23254288
http://dx.doi.org/10.1038/cddis.2012.182

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