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Immunoglobulin heavy/light chain ratios improve paraprotein detection and monitoring, identify residual disease and correlate with survival in multiple myeloma patients

The novel heavy/light chain (HLC) assay was used for the detection and measurement of monoclonal immunoglobulins, response evaluation and prognostication. This test allows identification and quantification of the different light chain types of each immunoglobulin class (for example, IgGκ and IgGλ) a...

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Detalles Bibliográficos
Autores principales: Ludwig, H, Milosavljevic, D, Zojer, N, Faint, J M, Bradwell, A R, Hübl, W, Harding, S J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542627/
https://www.ncbi.nlm.nih.gov/pubmed/22955329
http://dx.doi.org/10.1038/leu.2012.197