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Protein flexibility, not disorder, is intrinsic to molecular recognition
An ‘intrinsically disordered protein’ (IDP) is assumed to be unfolded in the cell and perform its biological function in that state. We contend that most intrinsically disordered proteins are in fact proteins waiting for a partner (PWPs), parts of a multi-component complex that do not fold correctly...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Faculty of 1000 Ltd
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542771/ https://www.ncbi.nlm.nih.gov/pubmed/23361309 http://dx.doi.org/10.3410/B5-2 |