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ATAD5 regulates the lifespan of DNA replication factories by modulating PCNA level on the chromatin

Temporal and spatial regulation of the replication factory is important for efficient DNA replication. However, the underlying molecular mechanisms are not well understood. Here, we report that ATAD5 regulates the lifespan of replication factories. Reduced expression of ATAD5 extended the lifespan o...

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Detalles Bibliográficos
Autores principales:	Lee, Kyoo-young, Fu, Haiqing, Aladjem, Mirit I., Myung, Kyungjae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542800/ https://www.ncbi.nlm.nih.gov/pubmed/23277426 http://dx.doi.org/10.1083/jcb.201206084

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