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Visualization of Structural Changes Accompanying Activation of N-Methyl-d-aspartate (NMDA) Receptors Using Fast-scan Atomic Force Microscopy Imaging

NMDA receptors are widely expressed in the central nervous system and play a major role in excitatory synaptic transmission and plasticity. Here, we used atomic force microscopy (AFM) imaging to visualize activation-induced structural changes in the GluN1/GluN2A NMDA receptor reconstituted into a li...

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Detalles Bibliográficos
Autores principales: Suzuki, Yuki, Goetze, Tom A., Stroebel, David, Balasuriya, Dilshan, Yoshimura, Shige H., Henderson, Robert M., Paoletti, Pierre, Takeyasu, Kunio, Edwardson, J. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543027/
https://www.ncbi.nlm.nih.gov/pubmed/23223336
http://dx.doi.org/10.1074/jbc.M112.422311

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