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Collinearity of protease mutations in HIV-1 samples with high-level protease inhibitor class resistance

OBJECTIVES: To determine whether pan-protease inhibitor (PI)-resistant virus populations are composed predominantly of viruses with resistance to all PIs or of diverse virus populations with resistance to different subsets of PIs. METHODS: We performed deep sequencing of plasma virus samples from ni...

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Detalles Bibliográficos
Autores principales:	Babrzadeh, Farbod, Varghese, Vici, Pacold, Mary, Liu, Tommy F., Nyrén, Pål, Schiffer, Celia, Fessel, W. Jeffrey, Shafer, Robert W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543120/ https://www.ncbi.nlm.nih.gov/pubmed/23085775 http://dx.doi.org/10.1093/jac/dks409

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