Pressure mediated hypertrophy and mechanical stretch up-regulate expression of the long form of leptin receptor (ob-Rb) in rat cardiac myocytes

BACKGROUND: Hyperleptinemia is known to participate in cardiac hypertrophy and hypertension, but the relationship between pressure overload and leptin is poorly understood. We therefore examined the expression of leptin (ob) and the leptin receptor (ob-R) in the pressure-overloaded rat heart. We als...

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Detalles Bibliográficos
Autores principales: Matsui, Hiroki, Yokoyama, Tomoyuki, Tanaka, Chie, Sunaga, Hiroaki, Koitabashi, Norimichi, Takizawa, Takako, Arai, Masashi, Kurabayashi, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543168/
https://www.ncbi.nlm.nih.gov/pubmed/23270329
http://dx.doi.org/10.1186/1471-2121-13-37

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