Cargando…

Ubiquitination and sumoylation of the HTLV-2 Tax-2B protein regulate its NF-κB activity: a comparative study with the HTLV-1 Tax-1 protein

BACKGROUND: Retroviruses HTLV-1 and HTLV-2 have homologous genomic structures but differ significantly in pathogenicity. HTLV-1 is associated with Adult T cell Leukemia (ATL), whereas infection by HTLV-2 has no association with neoplasia. Transformation of T lymphocytes by HTLV-1 is linked to the ca...

Descripción completa

Detalles Bibliográficos
Autores principales:	Turci, Marco, Lodewick, Julie, Di Gennaro, Gianfranco, Rinaldi, Anne Sophie, Marin, Oriano, Diani, Erica, Sampaio, Carla, Bex, Françoise, Bertazzoni, Umberto, Romanelli, Maria Grazia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543174/ https://www.ncbi.nlm.nih.gov/pubmed/23217160 http://dx.doi.org/10.1186/1742-4690-9-102

Ejemplares similares

Comparative analysis of HTLV-1 and HTLV-2 post-translational modifications of Tax proteins in relation to their intracellular localization and activation of gene expression
por: Turci, Marco, et al.
Publicado: (2009)

Highlights on distinctive structural and functional properties of HTLV Tax proteins
por: Romanelli, Maria Grazia, et al.
Publicado: (2013)

Intracellular Localization and Cellular Factors Interaction of HTLV-1 and HTLV-2 Tax Proteins: Similarities and Functional Differences
por: Bertazzoni, Umberto, et al.
Publicado: (2011)

Move or Die: the Fate of the Tax Oncoprotein of HTLV-1
por: Lodewick, Julie, et al.
Publicado: (2011)

HTLV Tax-1 and Tax-2 proteins enhance interferon regulatory factor 3 dependent promoter activation
por: Diani, Erica, et al.
Publicado: (2014)

Comparison of Tax-1 and Tax-2B post-translational modifications using specific lysine mutants in relation to activation of NF-κB and intracellular localization
por: Turci, Marco, et al.
Publicado: (2011)

The importance of ubiquitination and sumoylation on the transforming activity of HTLV Tax-1 and Tax-2
por: Zane, Linda, et al.
Publicado: (2012)

Post-translational modifications of HTLV-1 Tax carboxy-terminal domain: role in cellular transformation
por: Lodewick, Julie, et al.
Publicado: (2014)

HTLV Deregulation of the NF-κB Pathway: An Update on Tax and Antisense Proteins Role
por: Fochi, Stefania, et al.
Publicado: (2018)

Cytoplasmic and nuclear events controlling Tax-mediated activation of the NF-κB pathway: involvement of TAB2, IKKgamma/NEMO and calreticulin
por: Bex, Françoise, et al.
Publicado: (2011)

Acetylation at lysine 346 controls the transforming activity of the HTLV-1 Tax oncoprotein in the Rat-1 fibroblast model
por: Lodewick, Julie, et al.
Publicado: (2013)

TRAF3 Is Required for NF-κB Pathway Activation Mediated by HTLV Tax Proteins
por: Fochi, Stefania, et al.
Publicado: (2019)

NF-κB and MicroRNA Deregulation Mediated by HTLV-1 Tax and HBZ
por: Fochi, Stefania, et al.
Publicado: (2019)

IKKepsilon involvement in Tax-mediated activation of INF pathway
por: Cremonese, Giorgia, et al.
Publicado: (2011)

The HTLV-1 Tax interactome
por: Boxus, Mathieu, et al.
Publicado: (2008)

Post-translational modifications of the Tax oncoprotein of human T-cell leukemia virus control cytoplasmic and nuclear steps in Tax-mediated activation of the NF-κB pathway
por: Bex, Françoise, et al.
Publicado: (2009)

Expression and purification of the HTLV-1 transforming protein Tax
por: Evans, Whitney, et al.
Publicado: (2011)

Molecular characterization of a Tax-2C protein variant identified in Brazilian subjects infected by HTLV-2C
por: Caterino-de-Araujo, Adele, et al.
Publicado: (2014)

SUV39H1 interacts with HTLV-1 Tax and abrogates Tax transactivation of HTLV-1 LTR
por: Kamoi, Koju, et al.
Publicado: (2006)

Mechanisms of Oncogenesis by HTLV-1 Tax
por: Mohanty, Suchitra, et al.
Publicado: (2020)

An interaction map for HTLV-1 Tax and PDZ-containing proteins
por: Blibek, Karim, et al.
Publicado: (2014)

HTLV-1 Tax targets centrosomal Cep63 protein
por: Martin, Emilie, et al.
Publicado: (2015)

Distinct activities of HTLV-1 Tax1 from HTLV-2 Tax2 play key roles in pathogenesis
por: Fujii, Masahiro, et al.
Publicado: (2011)

Low levels of HTLV-2 Tax conjugation to ubiquitin and SUMO do not impede Tax-mediated activation of NF-κB
por: Journo, Chloé, et al.
Publicado: (2014)

Comparison of the Genetic Organization, Expression Strategies and Oncogenic Potential of HTLV-1 and HTLV-2
por: Rende, Francesca, et al.
Publicado: (2012)

HTLV-1 Tax: centrosome amplification and cancer
por: Pumfery, Anne, et al.
Publicado: (2006)

Distinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesis
por: Higuchi, Masaya, et al.
Publicado: (2009)

NF-kappaB activation: Tax sumoylation is out, but what about Tax ubiquitination?
por: Xiao, Gutian
Publicado: (2012)

The HTLV-1 oncoprotein Tax is modified by the ubiquitin related modifier 1 (Urm1)
por: Hleihel, Rita, et al.
Publicado: (2018)

Regulation of HTLV-1 Tax Stability, Cellular Trafficking and NF-κB Activation by the Ubiquitin-Proteasome Pathway
por: Lavorgna, Alfonso, et al.
Publicado: (2014)

Interference of HTLV-1 Tax Protein with Cell Polarity Regulators: Defining the Subcellular Localization of the Tax-DLG1 Interaction
por: Marziali, Federico, et al.
Publicado: (2017)

Direct Inhibition of RNAse T2 Expression by the HTLV-1 Viral Protein Tax
por: Polakowski, Nicholas, et al.
Publicado: (2011)

Nonsense-mediated mRNA decay inhibition by HTLV-1 Tax protein
por: Mocquet, Vincent, et al.
Publicado: (2014)

Induction of galectin-1 expression by HTLV-I Tax and its impact on HTLV-I infectivity
por: Gauthier, Sonia, et al.
Publicado: (2008)

Expression of the HBZ and tax genes of HTLV-1in infective dermatitis associated with HTLV-I (IDH)
por: Batista, Everton S, et al.
Publicado: (2011)

Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2
por: Shoji, Toshiyuki, et al.
Publicado: (2009)

A specificity map for HTLV-1 Tax/PDZ interactions
por: Blibek, Karim, et al.
Publicado: (2011)

Transformation of human embryonic stem cells by HTLV-1 Tax
por: Zane, Linda, et al.
Publicado: (2011)

Role of HTLV-1 Tax and HBZ in the Pathogenesis of HAM/TSP
por: Enose-Akahata, Yoshimi, et al.
Publicado: (2017)

Tax-mediated re-routing of the HTLV-1 p13 protein to nuclear speckles
por: Andresen, Vibeke, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_hamc8qnniji3fshh051gvihknj