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How deep is deep enough for RNA-Seq profiling of bacterial transcriptomes?
BACKGROUND: High-throughput sequencing of cDNA libraries (RNA-Seq) has proven to be a highly effective approach for studying bacterial transcriptomes. A central challenge in designing RNA-Seq-based experiments is estimating a priori the number of reads per sample needed to detect and quantify thousa...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543199/ https://www.ncbi.nlm.nih.gov/pubmed/23270466 http://dx.doi.org/10.1186/1471-2164-13-734 |